{"bekendtgoerelseNoegle":{"noticeId":{"value":"d05ef691-6ee9-4eb1-b6e6-b3b2cf67cfa0"},"noticeVersion":{"value":"02"},"noticePublicationNumber":{"value":"00652494-2025"}},"htmlDA":"\n\n \n
1 Køber
1.1 Køber
Officielt navn: Aalborg Universitet
\n
\n
\n
2 Procedure
2.1 Procedure
Titel: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
Beskrivelse: Our research is focused on developing EV-based biomarkers that are clinically applicable.\n For this, we have developed a method for measuring and characterizing nanosized particles,\n extracellular vesicles (EVs), directly in patient plasma samples (several published\n papers, one currently in review and several in preparation), requiring the highest\n level of sensitivity in a robust system is stable over time. To deliver EV-based research\n on the highest level, sensitivity, calibration, and standardization are of the essence\n when using high-resolution flow cytometry and a necessity when analyzing EVs.
Moreover,\n since our research is clinically based, why we need the capacity to run multiple samples\n every day, by running samples on two instruments simultaneously. We thus, need a high-resolution\n flow cytometer that deliver data, directly comparable with our current instrument.
In\n addition, we are currently developing methods for isolation of tissue-specific EV-populations\n to expand both insight in their involvement in tissue-specific diseases and thus,\n advance the future use of EV-based functional biomarker for detecting tissue-specific\n complications. Here an EV-sorter is a game changer that will significantly improve\n our research outcome by providing purification (sorting) of highly specific and pure\n EV-populations.
We thus need a high-resolution flow cytometer and EV-sorter that\n combines the level of resolution (in particular on light scatter), stability (doi:\n 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function),\n delivery of data that is directly comparable to current (to run clinical studies with\n a size (sample numbers) to deliver the necessary statistical power, needed for advancing\n EV-biomarker development) and sorter function that our research projects requires.\n The Apogee instrument offers resolution using a third light scatter detector (medium\n angle range, MALS) offer the best resolution of populations (particle size resolution)\n by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model\n data acquisition electronics with tunable
digital pulse filtering, allowing the\n flow velocity to be slowed down to increase sensitivity (both light
scatter and\n fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally,\n Apogee offers a particle size meta parameter (light scatter calibration), which is\n a unique method patented by ApogeeFlow offering a relatively easy calibration to SI\n units. The Kairos sorter included in the Apogee system is the only sorter of its type\n on the market (patent applies) with an electric field driven microfluidic sorter,\n offering fast sorting of specific EV-populations
\n
Identifikator for proceduren: 32b173a0-a70d-4d26-a422-197f83b7ba1c
\n
Intern ID: aae0dd27-41f7-4358-ac87-a6cc121cbd03
\n
Udbudsprocedure: Udbud med forhandling uden forudgående offentliggørelse
\n
2.1.1 Formål
Kontraktens hovedformål: Varer
\n
Primær klassifikation (cpv): 38000000 Laboratorieudstyr, optisk udstyr og præcisionsudstyr (ikke briller)
\n
\n
2.1.2 Udførelsessted
Postadresse: Selma Lagerløfs Vej 249  
\n
By: Gistrup
\n
Postnummer: 9260
\n
Landsdel (NUTS): Nordjylland (DK050)
\n
Land: Danmark
\n
\n
2.1.4 Generelle oplysninger
Retsgrundlag:
\n
Direktiv 2014/24/EU
\n
\n
\n
\n
5 Delkontrakt
5.1 Teknisk ID for delkontrakten: LOT-0000
Titel: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
Beskrivelse: Our research is focused on developing EV-based biomarkers that are clinically applicable.\n For this, we have developed a method for measuring and characterizing nanosized particles,\n extracellular vesicles (EVs), directly in patient plasma samples (several published\n papers, one currently in review and several in preparation), requiring the highest\n level of sensitivity in a robust system is stable over time. To deliver EV-based research\n on the highest level, sensitivity, calibration, and standardization are of the essence\n when using high-resolution flow cytometry and a necessity when analyzing EVs.
Moreover,\n since our research is clinically based, why we need the capacity to run multiple samples\n every day, by running samples on two instruments simultaneously. We thus, need a high-resolution\n flow cytometer that deliver data, directly comparable with our current instrument.
In\n addition, we are currently developing methods for isolation of tissue-specific EV-populations\n to expand both insight in their involvement in tissue-specific diseases and thus,\n advance the future use of EV-based functional biomarker for detecting tissue-specific\n complications. Here an EV-sorter is a game changer that will significantly improve\n our research outcome by providing purification (sorting) of highly specific and pure\n EV-populations.
We thus need a high-resolution flow cytometer and EV-sorter that\n combines the level of resolution (in particular on light scatter), stability (doi:\n 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function),\n delivery of data that is directly comparable to current (to run clinical studies with\n a size (sample numbers) to deliver the necessary statistical power, needed for advancing\n EV-biomarker development) and sorter function that our research projects requires.\n The Apogee instrument offers resolution using a third light scatter detector (medium\n angle range, MALS) offer the best resolution of populations (particle size resolution)\n by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model\n data acquisition electronics with tunable
digital pulse filtering, allowing the\n flow velocity to be slowed down to increase sensitivity (both light
scatter and\n fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally,\n Apogee offers a particle size meta parameter (light scatter calibration), which is\n a unique method patented by ApogeeFlow offering a relatively easy calibration to SI\n units. The Kairos sorter included in the Apogee system is the only sorter of its type\n on the market (patent applies) with an electric field driven microfluidic sorter,\n offering fast sorting of specific EV-populations
\n
Intern ID: a189b50a-6215-4e4e-b4e5-32e7b965aa40
\n
5.1.1 Formål
Kontraktens hovedformål: Varer
\n
Primær klassifikation (cpv): 38000000 Laboratorieudstyr, optisk udstyr og præcisionsudstyr (ikke briller)
\n
\n
5.1.2 Udførelsessted
Postadresse: Selma Lagerløfs Vej 249  
\n
By: Gistrup
\n
Postnummer: 9260
\n
Landsdel (NUTS): Nordjylland (DK050)
\n
Land: Danmark
\n
Yderligere oplysninger: 
\n
\n
5.1.6 Generelle oplysninger
Indkøbsprojekt, der ikke finansieres med EU-midler
\n
Udbuddet er omfattet af aftalen om offentlige udbud (GPA): ja
\n
\n
5.1.15 Teknikker
Rammeaftale:
Ingen rammeaftale
\n
\n
Oplysninger om det dynamiske indkøbssystem:
Intet dynamisk indkøbssystem
\n
\n
\n
5.1.16 Yderligere oplysninger, mægling og gennemgang
Organisation med ansvar for klager: Klagenævnet for Udbud
\n
Organisation, der leverer supplerende oplysninger om udbudsproceduren: Aalborg Universitet
\n
Organisation, der leverer yderligere oplysninger om klageprocedurerne: Konkurrence- og Forbrugerstyrelsen
\n
Organisation, hvis budget anvendes til at betale for kontrakten: Aalborg Universitet
\n
\n
\n
\n
6 Resultater
Direkte tildeling:
Begrundelse for direkte tildeling: Kontrakten kan kun tildeles af en bestemt økonomisk aktør på grund af manglende konkurrence af tekniske årsager
\n
Anden begrundelse: scatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis\n option. Finally, Apogee offers a particle size meta parameter (light scatter calibration),\n which is a unique method patented by ApogeeFlow offering a relatively easy calibration\n to SI units. The Kairos sorter included in the Apogee system is the only sorter of\n its type on the market (patent applies) with an electric field driven microfluidic\n sorter, offering fast sorting of specific EV-populations
\n
\n
6.1 Resultat delkontrakt-ID: LOT-0000
6.1.2 Oplysninger om vinderne
Vinder:
Officielt navn: Apogee Flow Systems Ltd
\n
Tilbud:
\n
Tilbud – Identifikator: Apogee Flow Systems Ltd
\n
ID for delkontrakt eller gruppe af delkontrakter: LOT-0000
\n
Værdien af tilbuddet: 2.058.175,11 Dansk krone
\n
Tilbuddet blev rangordnet: nej
\n
Kontraktoplysninger:
Identifikator for kontrakten: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
\n
\n
\n
\n
\n
8 Organisationer
8.1 ORG-0001
Officielt navn: Aalborg Universitet
\n
Registreringsnummer: 29102384
\n
Postadresse: Fredrik Bajers Vej 7K  
\n
By: Aalborg Øst
\n
Postnummer: 9220
\n
Landsdel (NUTS): Nordjylland (DK050)
\n
Land: Danmark
\n
Enhed: Alexander Herskind Rasmussen
\n
E-mail: ahra@adm.aau.dk
\n
Telefon: 22505186
\n
Denne organisations roller:
Køber
\n
Organisation, der leverer supplerende oplysninger om udbudsproceduren
\n
Organisation, hvis budget anvendes til at betale for kontrakten
\n
\n
\n
8.1 ORG-0002
Officielt navn: Klagenævnet for Udbud
\n
Registreringsnummer: 37795526
\n
Postadresse: Toldboden 2  
\n
By: Viborg
\n
Postnummer: 8800
\n
Landsdel (NUTS): Vestjylland (DK041)
\n
Land: Danmark
\n
Enhed: Klagenævnet for Udbud
\n
E-mail: klfu@naevneneshus.dk
\n
Telefon: +45 72405600
\n
Adresse til udveksling af oplysninger (URL) (eDelivery-Gateway): https://naevneneshus.dk/start-din-klage/klagenaevnet-for-udbud/
\n
Denne organisations roller:
Organisation med ansvar for klager
\n
\n
\n
8.1 ORG-0003
Officielt navn: Konkurrence- og Forbrugerstyrelsen
\n
Registreringsnummer: 10294819
\n
Postadresse: Carl Jacobsens Vej 35  
\n
By: Valby
\n
Postnummer: 2500
\n
Landsdel (NUTS): Byen København (DK011)
\n
Land: Danmark
\n
Enhed: Konkurrence- og Forbrugerstyrelsen
\n
E-mail: kfst@kfst.dk
\n
Telefon: +45 41715000
\n
Adresse til udveksling af oplysninger (URL) (eDelivery-Gateway): https://www.kfst.dk
\n
Denne organisations roller:
Organisation, der leverer yderligere oplysninger om klageprocedurerne
\n
\n
\n
8.1 ORG-0004
Officielt navn: Apogee Flow Systems Ltd
\n
Postadresse: 25 Ross Way  
\n
By: Northwood
\n
Postnummer: HA6 3HU
\n
Land: Det Forenede Kongerige
\n
Denne organisations roller:
Tilbudsgiver
\n
Vinder af disse delkontrakter: LOT-0000
\n
\n
\n
8.1 ORG-0005
Officielt navn: Mercell Holding ASA
\n
Registreringsnummer: 980921565
\n
Postadresse: Askekroken 11  
\n
By: Oslo
\n
Postnummer: 0277
\n
Landsdel (NUTS): Oslo (NO081)
\n
Land: Norge
\n
Enhed: eSender
\n
E-mail: publication@mercell.com
\n
Telefon: +47 21018800
\n
Fax: +47 21018801
\n
Internetadresse: http://mercell.com/
\n
Denne organisations roller:
TED eSender
\n
\n
\n
\n
Oplysninger om bekendtgørelsen
Bekendtgørelsens ID: d05ef691-6ee9-4eb1-b6e6-b3b2cf67cfa0 - 02
\n
Formulartype: Forudgående underretning om direkte tildeling
\n
Bekendtgørelsestype: Bekendtgørelse med henblik på frivillig forudgående gennemsigtighed
\n
Afsendelsesdato for bekendtgørelsen: 03-10-2025 09:26 +00:00
\n
Dato for afsendelse af bekendtgørelsen (eSender): 03-10-2025 09:27 +00:00
\n
Bekendtgørelsens officielle sprog: engelsk 
\n
Bekendtgørelsesnummer: 00652494-2025
\n
EUT-S-nummer: 191/2025
\n
Offentliggørelsesdato: 06-10-2025
\n
\n \n","htmlEN":"\n\n \n
1 Buyer
1.1 Buyer
Official name: Aalborg Universitet
\n
\n
\n
2 Procedure
2.1 Procedure
Title: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
Description: Our research is focused on developing EV-based biomarkers that are clinically applicable.\n For this, we have developed a method for measuring and characterizing nanosized particles,\n extracellular vesicles (EVs), directly in patient plasma samples (several published\n papers, one currently in review and several in preparation), requiring the highest\n level of sensitivity in a robust system is stable over time. To deliver EV-based research\n on the highest level, sensitivity, calibration, and standardization are of the essence\n when using high-resolution flow cytometry and a necessity when analyzing EVs.
Moreover,\n since our research is clinically based, why we need the capacity to run multiple samples\n every day, by running samples on two instruments simultaneously. We thus, need a high-resolution\n flow cytometer that deliver data, directly comparable with our current instrument.
In\n addition, we are currently developing methods for isolation of tissue-specific EV-populations\n to expand both insight in their involvement in tissue-specific diseases and thus,\n advance the future use of EV-based functional biomarker for detecting tissue-specific\n complications. Here an EV-sorter is a game changer that will significantly improve\n our research outcome by providing purification (sorting) of highly specific and pure\n EV-populations.
We thus need a high-resolution flow cytometer and EV-sorter that\n combines the level of resolution (in particular on light scatter), stability (doi:\n 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function),\n delivery of data that is directly comparable to current (to run clinical studies with\n a size (sample numbers) to deliver the necessary statistical power, needed for advancing\n EV-biomarker development) and sorter function that our research projects requires.\n The Apogee instrument offers resolution using a third light scatter detector (medium\n angle range, MALS) offer the best resolution of populations (particle size resolution)\n by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model\n data acquisition electronics with tunable
digital pulse filtering, allowing the\n flow velocity to be slowed down to increase sensitivity (both light
scatter and\n fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally,\n Apogee offers a particle size meta parameter (light scatter calibration), which is\n a unique method patented by ApogeeFlow offering a relatively easy calibration to SI\n units. The Kairos sorter included in the Apogee system is the only sorter of its type\n on the market (patent applies) with an electric field driven microfluidic sorter,\n offering fast sorting of specific EV-populations
\n
Procedure identifier: 32b173a0-a70d-4d26-a422-197f83b7ba1c
\n
Internal identifier: aae0dd27-41f7-4358-ac87-a6cc121cbd03
\n
Type of procedure: Negotiated without prior call for competition
\n
2.1.1 Purpose
Main nature of the contract: Supplies
\n
Main classification (cpv): 38000000 Laboratory, optical and precision equipments (excl. glasses)
\n
\n
2.1.2 Place of performance
Postal address: Selma Lagerløfs Vej 249  
\n
Town: Gistrup
\n
Postcode: 9260
\n
Country subdivision (NUTS): Nordjylland (DK050)
\n
Country: Denmark
\n
\n
2.1.4 General information
Legal basis:
\n
Directive 2014/24/EU
\n
\n
\n
\n
5 Lot
5.1 Lot technical ID: LOT-0000
Title: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
Description: Our research is focused on developing EV-based biomarkers that are clinically applicable.\n For this, we have developed a method for measuring and characterizing nanosized particles,\n extracellular vesicles (EVs), directly in patient plasma samples (several published\n papers, one currently in review and several in preparation), requiring the highest\n level of sensitivity in a robust system is stable over time. To deliver EV-based research\n on the highest level, sensitivity, calibration, and standardization are of the essence\n when using high-resolution flow cytometry and a necessity when analyzing EVs.
Moreover,\n since our research is clinically based, why we need the capacity to run multiple samples\n every day, by running samples on two instruments simultaneously. We thus, need a high-resolution\n flow cytometer that deliver data, directly comparable with our current instrument.
In\n addition, we are currently developing methods for isolation of tissue-specific EV-populations\n to expand both insight in their involvement in tissue-specific diseases and thus,\n advance the future use of EV-based functional biomarker for detecting tissue-specific\n complications. Here an EV-sorter is a game changer that will significantly improve\n our research outcome by providing purification (sorting) of highly specific and pure\n EV-populations.
We thus need a high-resolution flow cytometer and EV-sorter that\n combines the level of resolution (in particular on light scatter), stability (doi:\n 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function),\n delivery of data that is directly comparable to current (to run clinical studies with\n a size (sample numbers) to deliver the necessary statistical power, needed for advancing\n EV-biomarker development) and sorter function that our research projects requires.\n The Apogee instrument offers resolution using a third light scatter detector (medium\n angle range, MALS) offer the best resolution of populations (particle size resolution)\n by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model\n data acquisition electronics with tunable
digital pulse filtering, allowing the\n flow velocity to be slowed down to increase sensitivity (both light
scatter and\n fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally,\n Apogee offers a particle size meta parameter (light scatter calibration), which is\n a unique method patented by ApogeeFlow offering a relatively easy calibration to SI\n units. The Kairos sorter included in the Apogee system is the only sorter of its type\n on the market (patent applies) with an electric field driven microfluidic sorter,\n offering fast sorting of specific EV-populations
\n
Internal identifier: a189b50a-6215-4e4e-b4e5-32e7b965aa40
\n
5.1.1 Purpose
Main nature of the contract: Supplies
\n
Main classification (cpv): 38000000 Laboratory, optical and precision equipments (excl. glasses)
\n
\n
5.1.2 Place of performance
Postal address: Selma Lagerløfs Vej 249  
\n
Town: Gistrup
\n
Postcode: 9260
\n
Country subdivision (NUTS): Nordjylland (DK050)
\n
Country: Denmark
\n
Additional information: 
\n
\n
5.1.6 General information
Procurement Project not financed with EU Funds.
\n
The procurement is covered by the Government Procurement Agreement (GPA): yes
\n
\n
5.1.15 Techniques
Framework agreement:
No framework agreement
\n
\n
Information about the dynamic purchasing system:
No dynamic purchase system
\n
\n
\n
5.1.16 Further information, mediation and review
Review organisation: Klagenævnet for Udbud
\n
Organisation providing additional information about the procurement procedure: Aalborg Universitet
\n
Organisation providing more information on the review procedures: Konkurrence- og Forbrugerstyrelsen
\n
Organisation whose budget is used to pay for the contract: Aalborg Universitet
\n
\n
\n
\n
6 Results
Direct award:
Justification for direct award: The contract can be provided only by a particular economic operator because of an absence of competition for technical reasons
\n
Other justification: scatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis\n option. Finally, Apogee offers a particle size meta parameter (light scatter calibration),\n which is a unique method patented by ApogeeFlow offering a relatively easy calibration\n to SI units. The Kairos sorter included in the Apogee system is the only sorter of\n its type on the market (patent applies) with an electric field driven microfluidic\n sorter, offering fast sorting of specific EV-populations
\n
\n
6.1 Result lot ldentifier: LOT-0000
6.1.2 Information about winners
Winner:
Official name: Apogee Flow Systems Ltd
\n
Tender:
\n
Tender identifier: Apogee Flow Systems Ltd
\n
Identifier of lot or group of lots: LOT-0000
\n
Value of the tender: 2.058.175,11 Danish krone
\n
The tender was ranked: no
\n
Contract information:
Identifier of the contract: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module
\n
\n
\n
\n
\n
\n
8 Organisations
8.1 ORG-0001
Official name: Aalborg Universitet
\n
Registration number: 29102384
\n
Postal address: Fredrik Bajers Vej 7K  
\n
Town: Aalborg Øst
\n
Postcode: 9220
\n
Country subdivision (NUTS): Nordjylland (DK050)
\n
Country: Denmark
\n
Contact point: Alexander Herskind Rasmussen
\n
Email: ahra@adm.aau.dk
\n
Telephone: 22505186
\n
Roles of this organisation:
Buyer
\n
Organisation providing additional information about the procurement procedure
\n
Organisation whose budget is used to pay for the contract
\n
\n
\n
8.1 ORG-0002
Official name: Klagenævnet for Udbud
\n
Registration number: 37795526
\n
Postal address: Toldboden 2  
\n
Town: Viborg
\n
Postcode: 8800
\n
Country subdivision (NUTS): Vestjylland (DK041)
\n
Country: Denmark
\n
Contact point: Klagenævnet for Udbud
\n
Email: klfu@naevneneshus.dk
\n
Telephone: +45 72405600
\n
Information exchange endpoint (URL): https://naevneneshus.dk/start-din-klage/klagenaevnet-for-udbud/
\n
Roles of this organisation:
Review organisation
\n
\n
\n
8.1 ORG-0003
Official name: Konkurrence- og Forbrugerstyrelsen
\n
Registration number: 10294819
\n
Postal address: Carl Jacobsens Vej 35  
\n
Town: Valby
\n
Postcode: 2500
\n
Country subdivision (NUTS): Byen København (DK011)
\n
Country: Denmark
\n
Contact point: Konkurrence- og Forbrugerstyrelsen
\n
Email: kfst@kfst.dk
\n
Telephone: +45 41715000
\n
Information exchange endpoint (URL): https://www.kfst.dk
\n
Roles of this organisation:
Organisation providing more information on the review procedures
\n
\n
\n
8.1 ORG-0004
Official name: Apogee Flow Systems Ltd
\n
Postal address: 25 Ross Way  
\n
Town: Northwood
\n
Postcode: HA6 3HU
\n
Country: United Kingdom
\n
Roles of this organisation:
Tenderer
\n
Winner of these lots: LOT-0000
\n
\n
\n
8.1 ORG-0005
Official name: Mercell Holding ASA
\n
Registration number: 980921565
\n
Postal address: Askekroken 11  
\n
Town: Oslo
\n
Postcode: 0277
\n
Country subdivision (NUTS): Oslo (NO081)
\n
Country: Norway
\n
Contact point: eSender
\n
Email: publication@mercell.com
\n
Telephone: +47 21018800
\n
Fax: +47 21018801
\n
Internet address: http://mercell.com/
\n
Roles of this organisation:
TED eSender
\n
\n
\n
\n
Notice information
Notice identifier/version: d05ef691-6ee9-4eb1-b6e6-b3b2cf67cfa0 - 02
\n
Form type: Direct award preannouncement
\n
Notice type: Voluntary ex-ante transparency notice
\n
Notice dispatch date: 03-10-2025 09:26 +00:00
\n
Notice dispatch date (eSender): 03-10-2025 09:27 +00:00
\n
Languages in which this notice is officially available: English 
\n
Notice publication number: 00652494-2025
\n
OJ S issue number: 191/2025
\n
Publication date: 06-10-2025
\n
\n \n","opsummeringDA":{"card":{"titel":"A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module","ordregiver":"Aalborg Universitet","ordregiverId":"ORG-29102384","ordregiverIdDatavasket":"29102384","publiceringsdato":"2025-10-06+02:00","cpvKode":"38000000","cpvTitel":"Laboratorieudstyr, optisk udstyr og præcisionsudstyr (ikke briller)","formulartype":"Forudgående underretning om direkte tildeling","formulartypeKode":"dir-awa-pre","tidsfrister":[],"alleOrdregivere":["Aalborg Universitet"],"beskrivelse":"Our research is focused on developing EV-based biomarkers that are clinically applicable. For this, we have developed a method for measuring and characterizing nanosized particles, extracellular vesicles (EVs), directly in patient plasma samples (several published papers, one currently in review and several in preparation), requiring the highest level of sensitivity in a robust system is stable over time. To deliver EV-based research on the highest level, sensitivity, calibration, and standardization are of the essence when using high-resolution flow cytometry and a necessity when analyzing EVs.\nMoreover, since our research is clinically based, why we need the capacity to run multiple samples every day, by running samples on two instruments simultaneously. We thus, need a high-resolution flow cytometer that deliver data, directly comparable with our current instrument.\nIn addition, we are currently developing methods for isolation of tissue-specific EV-populations to expand both insight in their involvement in tissue-specific diseases and thus, advance the future use of EV-based functional biomarker for detecting tissue-specific complications. Here an EV-sorter is a game changer that will significantly improve our research outcome by providing purification (sorting) of highly specific and pure EV-populations.\nWe thus need a high-resolution flow cytometer and EV-sorter that combines the level of resolution (in particular on light scatter), stability (doi: 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function), delivery of data that is directly comparable to current (to run clinical studies with a size (sample numbers) to deliver the necessary statistical power, needed for advancing EV-biomarker development) and sorter function that our research projects requires. The Apogee instrument offers resolution using a third light scatter detector (medium angle range, MALS) offer the best resolution of populations (particle size resolution) by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model data acquisition electronics with tunable \ndigital pulse filtering, allowing the flow velocity to be slowed down to increase sensitivity (both light \nscatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally, Apogee offers a particle size meta parameter (light scatter calibration), which is a unique method patented by ApogeeFlow offering a relatively easy calibration to SI units. The Kairos sorter included in the Apogee system is the only sorter of its type on the market (patent applies) with an electric field driven microfluidic sorter, offering fast sorting of specific EV-populations","bkSubTypeKode":"25","bkSubType":"Bekendtgørelse med henblik på frivillig forudgående gennemsigtighed – det generelle direktiv","erAendring":false},"indholdsType":"HENTET_FRA_TED","sekundaereOrdregivere":[],"udforelsesstedNutsCode":["DK050"],"udforelsesstedSubLand":["Nordjylland"],"udforelsesstedLand":["Danmark"],"udforelsesstedBy":["Gistrup"],"tilbudsfrister":[],"intressentfrister":[],"deltagelsefrister":[],"svarfrister":[],"antalParts":0,"antalLots":1,"udbudsDokumenter":[]},"opsummeringEN":{"card":{"titel":"A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module","ordregiver":"Aalborg Universitet","ordregiverId":"ORG-29102384","ordregiverIdDatavasket":"29102384","publiceringsdato":"2025-10-06+02:00","cpvKode":"38000000","cpvTitel":"Laboratory, optical and precision equipments (excl. glasses)","formulartype":"Direct award preannouncement","formulartypeKode":"dir-awa-pre","tidsfrister":[],"alleOrdregivere":["Aalborg Universitet"],"beskrivelse":"Our research is focused on developing EV-based biomarkers that are clinically applicable. For this, we have developed a method for measuring and characterizing nanosized particles, extracellular vesicles (EVs), directly in patient plasma samples (several published papers, one currently in review and several in preparation), requiring the highest level of sensitivity in a robust system is stable over time. To deliver EV-based research on the highest level, sensitivity, calibration, and standardization are of the essence when using high-resolution flow cytometry and a necessity when analyzing EVs.\nMoreover, since our research is clinically based, why we need the capacity to run multiple samples every day, by running samples on two instruments simultaneously. We thus, need a high-resolution flow cytometer that deliver data, directly comparable with our current instrument.\nIn addition, we are currently developing methods for isolation of tissue-specific EV-populations to expand both insight in their involvement in tissue-specific diseases and thus, advance the future use of EV-based functional biomarker for detecting tissue-specific complications. Here an EV-sorter is a game changer that will significantly improve our research outcome by providing purification (sorting) of highly specific and pure EV-populations.\nWe thus need a high-resolution flow cytometer and EV-sorter that combines the level of resolution (in particular on light scatter), stability (doi: 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function), delivery of data that is directly comparable to current (to run clinical studies with a size (sample numbers) to deliver the necessary statistical power, needed for advancing EV-biomarker development) and sorter function that our research projects requires. The Apogee instrument offers resolution using a third light scatter detector (medium angle range, MALS) offer the best resolution of populations (particle size resolution) by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model data acquisition electronics with tunable \ndigital pulse filtering, allowing the flow velocity to be slowed down to increase sensitivity (both light \nscatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally, Apogee offers a particle size meta parameter (light scatter calibration), which is a unique method patented by ApogeeFlow offering a relatively easy calibration to SI units. The Kairos sorter included in the Apogee system is the only sorter of its type on the market (patent applies) with an electric field driven microfluidic sorter, offering fast sorting of specific EV-populations","bkSubTypeKode":"25","bkSubType":"Voluntary ex-ante transparency notice – general directive","erAendring":false},"indholdsType":"HENTET_FRA_TED","sekundaereOrdregivere":[],"udforelsesstedNutsCode":["DK050"],"udforelsesstedSubLand":["Nordjylland"],"udforelsesstedLand":["Denmark"],"udforelsesstedBy":["Gistrup"],"tilbudsfrister":[],"intressentfrister":[],"deltagelsefrister":[],"svarfrister":[],"antalParts":0,"antalLots":1,"udbudsDokumenter":[]}}