5 Delkontrakt

5.1 Teknisk ID for partiet: LOT-0000

Titel: Mass spectrometry systems for proteomics and bioimaging

Beskrivelse: Bruker MS package: Bruker timsTOF Ultra2 (including upgrade timsTOF Ultra2 in 2025)\n Bruker neofleX MALDI TOF-TOF MS/MS Upgrade of timsTOF Pro2 to next-generation timsTOF\n HT in 2025 Service agreement for Bruker timsTOF fleX instrument

Intern identifikator: 335832

5.1.1 Formål

Kontraktens art: Varer

Primær klassificering (cpv): 38000000 Laboratorieudstyr, optisk udstyr og præcisionsudstyr (ikke briller)

5.1.2 Udførelsessted

Postadresse: Syddansk Universitet

By: Odense

Postnummer: 5230

Landespecifik underafdeling (NUTS): Fyn (DK031)

Land: Danmark

Yderligere oplysninger:

5.1.6 Generelle oplysninger

Indkøbsprojekt, der ikke finansieres med EU-midler

Udbuddet er omfattet af aftalen om offentlige udbud (GPA): ja

Yderligere oplysninger: Bruker timsTOF Ultra2 is an electrospray ionization tandem mass spectrometer (ESI\n MS/MS) with unique capabilities, including next-generation, high-sensitivity CaptiveSpray\n Ultra2 ion source, trapped ion mobility separation (TIMS) in combination with hybrid\n quadrupole-time-of-flight (QTOF) mass analyzers. It allows for detection of low-input\n samples down to the single cell level.The TIMS module is unique as it enables gas-phase\n separation of molecule isomers, from modified peptides to intact, modified proteins,\n with a mass resolution >400, followed by MS/MS based sequencing of the biomolecules.The\n timsTOF Ultra2 allows for several unique high-sensitivity data acquitision modes based\n on the exclusive PASEF technology, including diaPASEF, midiaPASEF and prm-PASEF for\n proteomics applications. Bruker is the only manufacturer of ESI-TIMS-QTOF mass spectrometry\n systems with PASEF technology.The Bruker timsTOF Ultra2 will be upgraded to upcoming\n next-generation capabilities during 2025. This will support our research programs\n in top-down protein analysis and sequencing and in native protein analysis, as it\n expands the MS/MS capabilities of the instrument.Upgrade of Bruker timsTOF Pro2.The\n purchase includes an upgrade/exchange of existing timsTOF Pro2 instrument to the next-generation\n timsTOF HT by October 2025. This will boost our proteomics research program by affording\n enhanced sensitivity for analysis of small sample amounts from biological specimen,\n while allowing us to maintain the existing computational data analysis workflows.\n Changing to another platform would require major resources and time. Bruker neofleX\n TOF-TOF is a matrix-assisted laser desorption/ionization (MALDI) tandem mass spectrometer\n (MS/MS). This MALDI TOF-TOF system enables both mass analysis, MS/MS and molecular\n bioimaging. Top-down sequencing of intact proteins is possible. It also allows for\n MS imaging (MSI) analysis of biological specimen at 20 um spatial resolution at 20\n pixels/sec by accurate rastering a 10kHz pulsing UV laser across the sample stage\n using IntelliSlides. The software enables generation and representation of bioimages\n based on spatially resolved mass spectometry data. It is compatible with our existing\n software platform based on SCiLS Lab, Cardinal and RStudio. Changing to another platform\n would require major resources and time. These Bruker mass spectrometry systems will\n advance and expand research in molecular mass spectrometry imaging and in biomolecular\n mass spectrometry, including proteomics. The new Bruker timsTOF technology and its\n sensitivity, speed, and dynamic range is crucial for SDU's proteomics research program,\n especially as we prepare to analyze large biological and clinical sample cohorts (time\n course analysis, dose-response analysis, cell development/differentiation, biofluids,\n single cell analysis, etc). The precision required for comprehensive analysis aligns\n with the imminent challenge of measuring significant sample sets of peptides and proteins,\n underscoring the necessity for advanced ion mobility spectrometry and bioimaging capabilities.\n The equipment provides full integration into existing work routines, as it adds on\n to our existing Bruker timsTOF mass spectrometers, MS imaging sample preparation protocols,\n and data analysis workflows. A change of supplier will therefore require changes to\n established protocols and integrated software systems, which would be very resource\n intensive.

5.1.10 Tildelingskriterier

Kriterium:

Type: Pris

Beskrivelse: Price

Vægtning (procentdel, præcis): 100

5.1.12 Udbudsvilkår

Oplysninger om undersøgelsesfrister: According to the Act on the Complaints Board for Public Procurement, etc. (the law\n can be accessed at www.retsinformation.dk), the following deadlines apply for filing\n a complaint: A complaint regarding not being selected must be submitted to the Complaints\n Board for Public Procurement within 20 calendar days, cf. section 7(1) of the law,\n from the day after the notification is sent to the affected applicants regarding who\n has been selected, provided that the notification is accompanied by a justification\n for the decision in accordance with section 2(1), no. 1, of the law, and section 171(2)\n of the Public Procurement Act. In other cases, a complaint regarding procurement,\n cf. section 7(2) of the law, must be submitted to the Complaints Board for Public\n Procurement within: 45 calendar days after the contracting authority has published\n a notice in the Official Journal of the European Union announcing that a contract\n has been awarded. The deadline is calculated from the day after the notice has been\n published. 20 calendar days from the day after the contracting authority has communicated\n its decision, cf. section 185(2) of the Public Procurement Act. No later than at the\n same time a complaint is submitted to the Complaints Board for Public Procurement,\n the complainant must inform the contracting authority in writing that a complaint\n has been submitted to the Complaints Board for Public Procurement and whether the\n complaint has been filed during the standstill period, cf. section 6(4) of the law.\n In cases where the complaint is not filed during the standstill period, the complainant\n must also indicate whether a request is made for the suspensive effect of the complaint,\n cf. section 12(1) of the law. The email address of the Complaints Board for Public\n Procurement is listed in section VI.4.1). The Complaints Board for Public Procurement's\n complaints guide can be found at: www.erhvervsstyrelsen.dk.

5.1.15 Teknikker

Rammeaftale:

Ingen rammeaftale

Oplysninger om det dynamiske indkøbssystem:

Intet dynamisk indkøbssystem

5.1.16 Yderligere oplysninger, mægling og gennemgang

Organisation med ansvar for klager: Danish Complaints Board for Public Procurement

Organisation, der leverer yderligere oplysninger om klageprocedurerne: Danish Competition and Consumer Authority

TED eSender: Comdia ApS

6 Resultater

Værdien af alle kontrakter tildelt i denne meddelelse: 10.500.000 Dansk krone

Direkte tildeling:

Begrundelse for direkte tildeling: Kontrakten kan kun tildeles af en bestemt økonomisk aktør på grund af manglende konkurrence af tekniske årsager

Anden begrundelse: Public Procurement Act Section 80, litra 3 and 4 - Only one supplier: The mass spectrometry\n systems for proteomics and bioimaging can only be supplied by Bruker Nordic because\n it is the only known commercial supplier of a system with these technical specifications.\n There is an objective and proportionate reason for the establishment of specifications\n which result in there being only one supplier. The possibility that there are other\n potential suppliers who could deliver the same has been objectively excluded by market\n consultations.

6.1 Resultat delkontrakt-ID: LOT-0000

Der er udvalgt mindst én vinder.

6.1.2 Oplysninger om vinderne

Vinder:

Officielt navn: Bruker Nordic AB

Tilbud:

Tilbud – Identifikator: 1

Identifikator for delkontrakt eller gruppe af delkontrakter: LOT-0000

Værdien af resultatet: 10.500.000 Dansk krone

Underentrepriseværdien er kendt: nej

Underentrepriseprocentdelen er kendt: nej

Kontraktoplysninger:

Identifikator for kontrakten: 1

Titel: Mass spectrometry systems for proteomics and bioimaging

Datoen for udvælgelsen af det vindende tilbud: 16-09-2024

Dato for indgåelse af kontrakten: 30-09-2024

Kontrakten tildeles som led i en rammeaftale: nej

8 Organisationer

8.1 ORG-0001

Officielt navn: Syddansk Universitet

Registreringsnummer: 29283958

Postadresse: Campusvej 55

By: Odense M

Postnummer: 5230

Landespecifik underafdeling (NUTS): Fyn (DK031)

Land: Danmark

Kontaktpunkt: Cindie Arendal Petersen

E-mail: cap@sdu.dk

Telefon: +45 65509297

Internetadresse: https://www.sdu.dk/

Denne organisations roller:

Køber

8.1 ORG-0002

Officielt navn: Bruker Nordic AB

Registreringsnummer: SE556577236401

Postadresse: Torshamnsgatan 44

By: Kista

Postnummer: SE-16440

Land: Sverige

E-mail: willy.bjorklund@bruker.com

Telefon: +46 86552500

Denne organisations roller:

Tilbudsgiver

Vinder af disse delkontrakter: LOT-0000

8.1 ORG-1000

Officielt navn: Comdia ApS

Registreringsnummer: 33501404

Postadresse: Lindvedvej 73

By: Odense S

Postnummer: 5260

Landespecifik underafdeling (NUTS): Fyn (DK031)

Land: Danmark

E-mail: support@comdia.com

Telefon: +45 7199 3672

Internetadresse: https://www.comdia.com/

Denne organisations roller:

TED eSender

8.1 ORG-1001

Officielt navn: Danish Complaints Board for Public Procurement

Registreringsnummer: 37795526

Postadresse: Nævnenes Hus, Toldboden 2

By: Viborg

Postnummer: 8800

Landespecifik underafdeling (NUTS): Vestjylland (DK041)

Land: Danmark

E-mail: klfu@naevneneshus.dk

Telefon: +45 7240 5600

Internetadresse: http://www.klfu.dk

Denne organisations roller:

Organisation med ansvar for klager

8.1 ORG-1002

Officielt navn: Danish Competition and Consumer Authority

Registreringsnummer: 10294819

Postadresse: Carl Jacobsens Vej 35

By: Valby

Postnummer: 2500

Landespecifik underafdeling (NUTS): Københavns omegn (DK012)

Land: Danmark

E-mail: kfst@kfst.dk

Telefon: +45 4171 5000

Internetadresse: https://www.kfst.dk/

Denne organisations roller:

Organisation, der leverer yderligere oplysninger om klageprocedurerne

5 Lot

5.1 Lot technical ID: LOT-0000

Title: Mass spectrometry systems for proteomics and bioimaging

Description: Bruker MS package: Bruker timsTOF Ultra2 (including upgrade timsTOF Ultra2 in 2025)\n Bruker neofleX MALDI TOF-TOF MS/MS Upgrade of timsTOF Pro2 to next-generation timsTOF\n HT in 2025 Service agreement for Bruker timsTOF fleX instrument

Internal identifier: 335832

5.1.1 Purpose

Main nature of the contract: Supplies

Main classification (cpv): 38000000 Laboratory, optical and precision equipments (excl. glasses)

5.1.2 Place of performance

Postal address: Syddansk Universitet

Town: Odense

Postcode: 5230

Country subdivision (NUTS): Fyn (DK031)

Country: Denmark

Additional information:

5.1.6 General information

Procurement Project not financed with EU Funds.

The procurement is covered by the Government Procurement Agreement (GPA): yes

Additional information: Bruker timsTOF Ultra2 is an electrospray ionization tandem mass spectrometer (ESI\n MS/MS) with unique capabilities, including next-generation, high-sensitivity CaptiveSpray\n Ultra2 ion source, trapped ion mobility separation (TIMS) in combination with hybrid\n quadrupole-time-of-flight (QTOF) mass analyzers. It allows for detection of low-input\n samples down to the single cell level.The TIMS module is unique as it enables gas-phase\n separation of molecule isomers, from modified peptides to intact, modified proteins,\n with a mass resolution >400, followed by MS/MS based sequencing of the biomolecules.The\n timsTOF Ultra2 allows for several unique high-sensitivity data acquitision modes based\n on the exclusive PASEF technology, including diaPASEF, midiaPASEF and prm-PASEF for\n proteomics applications. Bruker is the only manufacturer of ESI-TIMS-QTOF mass spectrometry\n systems with PASEF technology.The Bruker timsTOF Ultra2 will be upgraded to upcoming\n next-generation capabilities during 2025. This will support our research programs\n in top-down protein analysis and sequencing and in native protein analysis, as it\n expands the MS/MS capabilities of the instrument.Upgrade of Bruker timsTOF Pro2.The\n purchase includes an upgrade/exchange of existing timsTOF Pro2 instrument to the next-generation\n timsTOF HT by October 2025. This will boost our proteomics research program by affording\n enhanced sensitivity for analysis of small sample amounts from biological specimen,\n while allowing us to maintain the existing computational data analysis workflows.\n Changing to another platform would require major resources and time. Bruker neofleX\n TOF-TOF is a matrix-assisted laser desorption/ionization (MALDI) tandem mass spectrometer\n (MS/MS). This MALDI TOF-TOF system enables both mass analysis, MS/MS and molecular\n bioimaging. Top-down sequencing of intact proteins is possible. It also allows for\n MS imaging (MSI) analysis of biological specimen at 20 um spatial resolution at 20\n pixels/sec by accurate rastering a 10kHz pulsing UV laser across the sample stage\n using IntelliSlides. The software enables generation and representation of bioimages\n based on spatially resolved mass spectometry data. It is compatible with our existing\n software platform based on SCiLS Lab, Cardinal and RStudio. Changing to another platform\n would require major resources and time. These Bruker mass spectrometry systems will\n advance and expand research in molecular mass spectrometry imaging and in biomolecular\n mass spectrometry, including proteomics. The new Bruker timsTOF technology and its\n sensitivity, speed, and dynamic range is crucial for SDU's proteomics research program,\n especially as we prepare to analyze large biological and clinical sample cohorts (time\n course analysis, dose-response analysis, cell development/differentiation, biofluids,\n single cell analysis, etc). The precision required for comprehensive analysis aligns\n with the imminent challenge of measuring significant sample sets of peptides and proteins,\n underscoring the necessity for advanced ion mobility spectrometry and bioimaging capabilities.\n The equipment provides full integration into existing work routines, as it adds on\n to our existing Bruker timsTOF mass spectrometers, MS imaging sample preparation protocols,\n and data analysis workflows. A change of supplier will therefore require changes to\n established protocols and integrated software systems, which would be very resource\n intensive.

5.1.10 Award criteria

Criterion:

Type: Price

Description: Price

Weight (percentage, exact): 100

5.1.12 Terms of procurement

Information about review deadlines: According to the Act on the Complaints Board for Public Procurement, etc. (the law\n can be accessed at www.retsinformation.dk), the following deadlines apply for filing\n a complaint: A complaint regarding not being selected must be submitted to the Complaints\n Board for Public Procurement within 20 calendar days, cf. section 7(1) of the law,\n from the day after the notification is sent to the affected applicants regarding who\n has been selected, provided that the notification is accompanied by a justification\n for the decision in accordance with section 2(1), no. 1, of the law, and section 171(2)\n of the Public Procurement Act. In other cases, a complaint regarding procurement,\n cf. section 7(2) of the law, must be submitted to the Complaints Board for Public\n Procurement within: 45 calendar days after the contracting authority has published\n a notice in the Official Journal of the European Union announcing that a contract\n has been awarded. The deadline is calculated from the day after the notice has been\n published. 20 calendar days from the day after the contracting authority has communicated\n its decision, cf. section 185(2) of the Public Procurement Act. No later than at the\n same time a complaint is submitted to the Complaints Board for Public Procurement,\n the complainant must inform the contracting authority in writing that a complaint\n has been submitted to the Complaints Board for Public Procurement and whether the\n complaint has been filed during the standstill period, cf. section 6(4) of the law.\n In cases where the complaint is not filed during the standstill period, the complainant\n must also indicate whether a request is made for the suspensive effect of the complaint,\n cf. section 12(1) of the law. The email address of the Complaints Board for Public\n Procurement is listed in section VI.4.1). The Complaints Board for Public Procurement's\n complaints guide can be found at: www.erhvervsstyrelsen.dk.

5.1.15 Techniques

Framework agreement:

No framework agreement

Information about the dynamic purchasing system:

No dynamic purchase system

5.1.16 Further information, mediation and review

Review organisation: Danish Complaints Board for Public Procurement

Organisation providing more information on the review procedures: Danish Competition and Consumer Authority

TED eSender: Comdia ApS

6 Results

Value of all contracts awarded in this notice: 10.500.000 Danish krone

Direct award:

Justification for direct award: The contract can be provided only by a particular economic operator because of an absence of competition for technical reasons

Other justification: Public Procurement Act Section 80, litra 3 and 4 - Only one supplier: The mass spectrometry\n systems for proteomics and bioimaging can only be supplied by Bruker Nordic because\n it is the only known commercial supplier of a system with these technical specifications.\n There is an objective and proportionate reason for the establishment of specifications\n which result in there being only one supplier. The possibility that there are other\n potential suppliers who could deliver the same has been objectively excluded by market\n consultations.

6.1 Result lot ldentifier: LOT-0000

At least one winner was chosen.

6.1.2 Information about winners

Winner:

Official name: Bruker Nordic AB

Tender:

Tender identifier: 1

Identifier of lot or group of lots: LOT-0000

Value of the result: 10.500.000 Danish krone

Subcontracting value is known: no

Subcontracting percentage is known: no

Contract information:

Identifier of the contract: 1

Title: Mass spectrometry systems for proteomics and bioimaging

Date on which the winner was chosen: 16-09-2024

Date of the conclusion of the contract: 30-09-2024

The contract is awarded within a framework agreement: no

8 Organisations

8.1 ORG-0001

Official name: Syddansk Universitet

Registration number: 29283958

Postal address: Campusvej 55

Town: Odense M

Postcode: 5230

Country subdivision (NUTS): Fyn (DK031)

Country: Denmark

Contact point: Cindie Arendal Petersen

Email: cap@sdu.dk

Telephone: +45 65509297

Internet address: https://www.sdu.dk/

Roles of this organisation:

Buyer

8.1 ORG-0002

Official name: Bruker Nordic AB

Registration number: SE556577236401

Postal address: Torshamnsgatan 44

Town: Kista

Postcode: SE-16440

Country: Sweden

Email: willy.bjorklund@bruker.com

Telephone: +46 86552500

Roles of this organisation:

Tenderer

Winner of these lots: LOT-0000

8.1 ORG-1000

Official name: Comdia ApS

Registration number: 33501404

Postal address: Lindvedvej 73

Town: Odense S

Postcode: 5260

Country subdivision (NUTS): Fyn (DK031)

Country: Denmark

Email: support@comdia.com

Telephone: +45 7199 3672

Internet address: https://www.comdia.com/

Roles of this organisation:

TED eSender

8.1 ORG-1001

Official name: Danish Complaints Board for Public Procurement

Registration number: 37795526

Postal address: Nævnenes Hus, Toldboden 2

Town: Viborg

Postcode: 8800

Country subdivision (NUTS): Vestjylland (DK041)

Country: Denmark

Email: klfu@naevneneshus.dk

Telephone: +45 7240 5600

Internet address: http://www.klfu.dk

Roles of this organisation:

Review organisation

8.1 ORG-1002

Official name: Danish Competition and Consumer Authority

Registration number: 10294819

Postal address: Carl Jacobsens Vej 35

Town: Valby

Postcode: 2500

Country subdivision (NUTS): Københavns omegn (DK012)

Country: Denmark

Email: kfst@kfst.dk

Telephone: +45 4171 5000

Internet address: https://www.kfst.dk/

Roles of this organisation:

Organisation providing more information on the review procedures